50 Fastest Growing Startups In San Diego [2024]

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Updated: May 31st, 2022

50 Fastest Growing Startups In San Diego [2024]

San Diego is one of the most vibrant and dynamic cities in California, which has brought various economic benefits to the community.

The lifestyle in San Diego is perhaps one of the best in the United States. San Diego consistently ranks high on quality-of-life indexes and is an excellent place for start-ups.

San Diego is a wonderful place to live, work and play. It's surrounded by the beautiful Pacific Ocean, and it's filled with amazing people full of entrepreneurial spirit.

In this article, we’ve compiled a list of the top 50 startups in San Diego that are making an impact in 2022.

Here they are:

#	Company	Funding	Revenue	Employees
1	ClickUp	$538M	$10M	800
2	Drata	$128M	$55.3M	153
3	Kandji	$188M	$56M	315
4	Flock Freight	$400M	$189M	455
5	Vuori Clothing	$445M	$65M	265
6	Biosplice	$800M	$26M	166
7	RayzeBio	$258M	$9.6M	62
8	Workiz	$60M	$14M	100
9	Shield AI	$348M	$98M	300
10	Tealium	$264M	$120M	678
11	TuSimple	$648M	$173M	860
12	Mosaic	$21M	$12.5M	90
13	JuneShine	$24M	$32.5M	120
14	Platform Science	$71M	$57.8M	245
15	Trovata	$30.6M	$12M	92
16	Cloudbeds	$249M	$196M	609
17	Netradyne	$198M	$60.8M	342
18	Element Biosciences	$401M	$39.2M	254
19	Sendlane	$24.5M	$8.6M	70
20	Daasity	$20.7M	$4.6M	45
21	Prometheus Biosciences	$452M	$2.6M	105
22	Vessel	$133M	$8.2M	67
23	Molecular Assemblies	$61.2M	$7.8M	50
24	Airspace	$66M	$96.7M	295
25	AttackIQ	$75.9M	$36.6M	168
26	Cue Health	$1B	$439M	810
27	Erasca	$300M	$22.3M	145
28	SOCi	$118M	$80.5M	453
29	Measurabl	$79.6M	$18.2M	130
30	Tiled	$141M	$7.8M	64
31	Classy	$184M	$60M	363
32	Miva Ecommerce Platform	$18M	$30.6M	196
33	NUVVE Corp	$18M	$20M	70
34	Liquid Instruments	$30M	$7.7M	64
35	SpineZone	$12M	$16.7M	71
36	Truepic	$36.5M	$7.1M	56
37	DermTech	$260M	$44.6M	288
38	Artiva	$198M	$7.1M	46
39	Bank of Southern California	$93M	$35M	155
40	Kinnate Biopharma	$195M	$13M	83
41	Bionano Genomics	$208M	$12M	270
42	Mirati Therapeutics	$2B	$73.5M	544
43	EcoATM	$347M	$68.5M	415
44	DTx Pharma	$114M	$8M	51
45	Blooma	$20.8M	$3.5M	32
46	Power Digital Marketing	$15M	$110M	616
47	Encodia	$75M	$14.3M	92
48	BlueNalu	$84.8M	$9.6M	47
49	Locana	$156M	$12M	78
50	GoFormz	$31.5M	$11M	76

1. ClickUp

Our mission is to make the world more productive. To do this, we built one app to replace them all - Tasks, Docs, Goals, and Chat.

Founded in: 2016
Funding: $538M
Revenue: $10M/year
Number of employees: 800

2. Drata

Drata is the fastest & simplest way to achieve continuous SOC 2 and ISO 27001 compliance. Build trust and securely grow your business.

Founded in: 2020
Funding: $128M
Revenue: $55.3M/year
Number of employees: 153

3. Kandji

The modern Apple device management solution for macOS, iOS, iPadOS, and tvOS. Apple MDM built for modern businesses.

Founded in: 2018
Funding: $188M
Revenue: $56M/year
Number of employees: 315

4. Flock Freight

Flock Freight exists to make the freight industry a better place for shippers, carriers, and the environment.

Founded in: 2015
Funding: $400M
Revenue: $189M/year
Number of employees: 455

5. Vuori Clothing

Providing a new perspective for athletic clothing, Vuori is built to move and sweat in, designed for an active lifestyle. Learn more today

Founded in: 2013
Funding: $445M
Revenue: $65M/year
Number of employees: 265

6. Biosplice

Biosplice’s mission is to restore health by delivering first-in-class therapies that harness alternative splicing.

Founded in: 2008
Funding: $800M
Revenue: $26M/year
Number of employees: 166

7. RayzeBio

RayzeBio is a pharmaceutical company that develops targeted radiopharmaceutical drugs for cancer.

Founded in: 2018
Funding: $258M
Revenue: $9.6M/year
Number of employees: 62

8. Workiz

Join 100K+ service pros who are already beating their competition with Workiz – service business management & scheduling software. Start for free today.

Founded in: 2015
Funding: $60M
Revenue: $14M/year
Number of employees: 100

9. Shield AI

We're building Hivemind, our AI pilot, to enable swarms of drones and aircraft to operate autonomously without GPS, communications, or a pilot.

Founded in: 2015
Funding: $348M
Revenue: $98M/year
Number of employees: 300

10. Tealium

All of your data. Fully integrated. Tealium’s Customer Data Hub connects your mobile, web, offline, and other data sources together with every vendor integration. Get to know your customers, identify untouched opportunities and deliver incredible customer experiences. Start connecting all of your data sources today.

Founded in: 2008
Funding: $264M
Revenue: $120M/year
Number of employees: 678

11. TuSimple

TuSimple builds the world's largest Autonomous Trucks and most advanced Driverless vehicles. Find self-driving freight trucking, Long Haul, Semi-trailer and autopilot systems.

Founded in: 2015
Funding: $648M
Revenue: $173M/year
Number of employees: 860

12. Mosaic

Mosaic offers a Strategic Finance Platform that provides real-time financial analytics and planning to get teams from data to decision — faster.

Founded in: 2019
Funding: $21M
Revenue: $12.5M/year
Number of employees: 90

13. JuneShine

Why do we know so much about the food we eat, but not the alcohol we drink? JuneShine is organic, sustainably-produced, 6% ABV hard kombucha with real ingredients.

Founded in: 2018
Funding: $24M
Revenue: $32.5M/year
Number of employees: 120

14. Platform Science

Platform Science is an innovative enterprise grade Iot fleet management platform for the transportation and logistics industry.

Founded in: 2015
Funding: $71M
Revenue: $57.8M/year
Number of employees: 245

15. Trovata

Trovata is an open banking platform: know instantly how much cash you have, automate cash management, forecast quickly, and manage cash flow with precision.

Founded in: 2016
Funding: $30.6M
Revenue: $12M/year
Number of employees: 92

16. Cloudbeds

Award-winning property management software that helps hotels, hostels, vacation rentals and inns save time and automate operations. One system, one login

Founded in: 2012
Funding: $249M
Revenue: $196M/year
Number of employees: 609

17. Netradyne

Netradyne’s Advanced AI fleet safety platform delivers unmatched visibility into fleet performance and the insights to make decisions.

Founded in: 2015
Funding: $198M
Revenue: $60.8M/year
Number of employees: 342

18. Element Biosciences

Our new benchtop sequencing platform - AVITI™ - allows scientists to transform their research from inquiry to insight to create tangible impact for the real world.

Founded in: 2017
Funding: $401M
Revenue: $39.2M/year
Number of employees: 254

19. Sendlane

Deliver Exceptional ECommerce Customer Experiences with Email and SMS for BigCommerce

Founded in: 2013
Funding: $24.5M
Revenue: $8.6M/year
Number of employees: 70

20. Daasity

Daasity helps over 1,600 consumer product brands unlock data-driven growth. One product. One data set. One view. Limitless potential. With Daasity, it’s one and done. Daasity is the only business insights solution built for direct-to-consumer brands by leaders in the eCommerce space.

Founded in: 2017
Funding: $20.7M
Revenue: $4.6M/year
Number of employees: 45

21. Prometheus Biosciences

Prometheus Biosciences is a biotechnology company specializing in developing precision therapies for immune-mediated diseases using a one-of-a-kind approach.

Founded in: 1995
Funding: $452M
Revenue: $2.6M/year
Number of employees: 105

22. Vessel

Take the guesswork out of your health. With custom nutrition plans, supplements formulated to your body, and personalized lifestyle hacks, it’s never been easier to perform at your best.

Founded in: 2017
Funding: $133M
Revenue: $8.2M/year
Number of employees: 67

23. Molecular Assemblies

Molecular Assemblies, Inc. is a private life sciences company developing an enzymatic DNA synthesis technology designed to power the next generation of DNA-based products. The Company’s patented enzymatic method, based on making DNA the way nature makes DNA, produces long, high quality, sequence-specific DNA reliably, affordably, and sustainably.

Founded in: 2013
Funding: $61.2M
Revenue: $7.8M/year
Number of employees: 50

24. Airspace

Airspace is a shipping service for critical, valuable items. Our technology and human care mean speed, tracking, and full transparency for your shipments.

Founded in: 2016
Funding: $66M
Revenue: $96.7M/year
Number of employees: 295

25. AttackIQ

The AttackIQ Security Optimization Platform enables a seamless threat-informed defense across your organization, improving efficiency and effectiveness.

Founded in: 2013
Funding: $75.9M
Revenue: $36.6M/year
Number of employees: 168

26. Cue Health

From COVID-19 to influenza, the Cue Health Monitoring System provides rapid, lab-quality molecular testing—anytime, anywhere.

Founded in: 2010
Funding: $1B
Revenue: $439M/year
Number of employees: 810

27. Erasca

Erasca is a clinical-stage precision oncology company driven by a bold mission to erase cancer.

Founded in: 2018
Funding: $300M
Revenue: $22.3M/year
Number of employees: 145

28. SOCi

SOCi is the leading all-in-one platform built for "next-level" multi-location marketers to reach & engage local customers across limitless locations.

Founded in: 2012
Funding: $118M
Revenue: $80.5M/year
Number of employees: 453

29. Measurabl

World's #1 ESG Software for Commercial Real Estate - investment grade sustainability data for corporate disclosure and transparency.

Founded in: 2013
Funding: $79.6M
Revenue: $18.2M/year
Number of employees: 130

30. Tiled

Tiled is an interactive content platform to create engaging experiences easily. Our no-code story builder lets enterprise sales, marketing, creative, and HR teams create, edit, and share interactive content from anywhere, anytime, with actionable analytics to scale impact.

Founded in: 2016
Funding: $141M
Revenue: $7.8M/year
Number of employees: 64

31. Classy

Classy is a giving platform that enables nonprofits to connect with supporters through online fundraising.

Founded in: 2006
Funding: $184M
Revenue: $60M/year
Number of employees: 363

32. Miva Ecommerce Platform

The most flexible & secure ecommerce software on the market. Build your online store today with a shopping cart platform by Miva Merchant.

Founded in: 1996
Funding: $18M
Revenue: $30.6M/year
Number of employees: 196

33. NUVVE Corp

Nuvve is the global leader in vehicle-to-grid (V2G) technology offering high-powered charging and grid services that optimize unused and renewable energy.

Founded in: 2010
Funding: $18M
Revenue: $20M/year
Number of employees: 70

34. Liquid Instruments

Redefining the way scientists, engineers, students, and professionals experience test and measurement with Moku software-reconfigurable hardware platforms

Founded in: 2014
Funding: $30M
Revenue: $7.7M/year
Number of employees: 64

35. SpineZone

The SpineZone Program, developed by spine specialists, relieves back and neck pain while minimizing the need for surgery, prescription drugs, or injections.

Founded in: 2005
Funding: $12M
Revenue: $16.7M/year
Number of employees: 71

36. Truepic

Truepic Vision is the leading virtual inspection platform. You can seamlessly request and view authenticated images from anywhere in the world.

Founded in: 2016
Funding: $36.5M
Revenue: $7.1M/year
Number of employees: 56

37. DermTech

Cut the uncertainty, not the patient. Introducing a truly non-invasive breakthrough in cancer detection. DermTech has developed a proprietary process to extract RNA from skin tissue samples collected non-invasively, using an adhesive patch.

Founded in: 2015
Funding: $260M
Revenue: $44.6M/year
Number of employees: 288

38. Artiva

Artiva Biotherapeutics is bringing together the best technologies in the world to advance cell therapy for cancer.

Founded in: 2019
Funding: $198M
Revenue: $7.1M/year
Number of employees: 46

39. Bank of Southern California

As Southern California's commercial bank, we are committed to providing our local businesses and individuals with personalized banking solutions.

Founded in: 2001
Funding: $93M
Revenue: $35M/year
Number of employees: 155

40. Kinnate Biopharma

Kinnate Biopharma is a precision oncology company focused on the design and development of selective small molecules targeting genetic mutations and fusions with no coverage currently.

Founded in: 2018
Funding: $195M
Revenue: $13M/year
Number of employees: 83

41. Bionano Genomics

Bionano Genomics provides unparalleled structural variation detection for genetic disease research, cancer research & cytogenomics with Optical Genome Mapping.

Founded in: 2003
Funding: $208M
Revenue: $12M/year
Number of employees: 270

42. Mirati Therapeutics

At Mirati, we are relentlessly focused on finding meaningful breakthroughs and targeted solutions for genetic and immunological drivers of cancer while fostering a culture of inclusion, collaboration, and innovation.

Founded in: 1995
Funding: $2B
Revenue: $73.5M/year
Number of employees: 544

43. EcoATM

ecoATM kiosks help you sell your old phones for instant cash! We make recycling & trade-ins of used devices safe & convenient.

Founded in: 2008
Funding: $347M
Revenue: $68.5M/year
Number of employees: 415

44. DTx Pharma

At DTx, we are a group of flexible, innovative thinkers who are determined to solve one of the biggest challenges limiting the development of genetic medicines.

Founded in: 2017
Funding: $114M
Revenue: $8M/year
Number of employees: 51

45. Blooma

Blooma delivers a radically different and modern way to do business. With automated underwriting, you can step back from monotonous and painstaking tasks and dive into data-driven insights that drive real results.

Founded in: 2018
Funding: $20.8M
Revenue: $3.5M/year
Number of employees: 32

46. Power Digital Marketing

Power is a full-service digital agency focused on growth-oriented marketing & increasing performance of digital channels. Contact us for an appraisal.

Founded in: 2012
Funding: $15M
Revenue: $110M/year
Number of employees: 616

47. Encodia

Encodia is a rapidly growing platform company that is developing a new generation of protein analysis tools based on single-molecule protein sequencing.

Founded in: 2015
Funding: $75M
Revenue: $14.3M/year
Number of employees: 92

48. BlueNalu

BlueNalu's mission is to be the global leader in cellular aquaculture, providing consumers with great tasting, healthy, safe, and trusted seafood products that support the sustainability and diversity of our oceans.

Founded in: 2017
Funding: $84.8M
Revenue: $9.6M/year
Number of employees: 47

49. Locana

Formerly Critigen, Locana is a world-class geospatial company with decades of experience combined with cutting-edge solutions. We're the future of location.

Founded in: 2016
Funding: $156M
Revenue: $12M/year
Number of employees: 78

50. GoFormz

Use the GoFormz mobile forms and data capture platform to fill out forms on mobile devices and computers, even offline. Your mobile forms can look exactly like your existing paper forms, and be used to collect images, gps, signatures and more. Sign up for a free account!

Founded in: 2012
Funding: $31.5M
Revenue: $11M/year
Number of employees: 76

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